Kelley F. Kitto
Assistant Scientist

Department of Neuroscience
Present PI Affiliations: George Wilcox, Carolyn Fairbanks
Years of University Contribution: 20
Awards: Patrick J. Manning


Fairbanks, CA, Posthumus, IJ, Kitto, KF, Stone, LS and Wilcox, GL (2000) Moxonidine, a selective imidazoline/a2 adrenergic receptor agonist, synergizes with morphine and deltorphin II to inhibit substance P-induced behavior in mice. Pain 84:13-20.

Fairbanks, CA, Schreiber, KL, Brewer, KL, Yu, CG, Stone, LS, Kitto, KF, Nguyen, HO, Grocholski, BM, Shoeman, DW, Kehl, LJ, Regunathan, S, Reis, DJ, Yezierski, RP and Wilcox, GL (2000) Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury. Proceedings of the National Academy of Sciences 97:19584-10589.

Fairbanks, CA, Stone, LS, Kitto, KF, Nguyen, HO, Posthumus, IJ and Wilcox, GL (in press) Alpha2C adrenergic receptors mediate spinal analgesia and adrenergic-opioid synergy. J. Pharmacol. Exp. Therap.

Giovengo, SL, Kitto, KF, Kurtz, HJ, Velazquez, RA and Larson, AA (1999) Parenterally administered kainic acid induces a persistent hyperalgesia in the mouse and rat. Pain 83:347-58.

Kitto, KF, Haley, JE and Wilcox, GL (1992) Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse. Neurosci. Lett. 148:1-5.

Larson, AA and Kitto, KF (1995) Sensitization to the behavioral effect of kainic acid in the mouse is mediated by nitric oxide. J. Pharmacol. Exp. Ther. 275:544-550.

Larson, AA and Kitto, KF (1997) Mutual antagonism between nerve growth factor and substance P N-terminal activity on nociceptive activity in mice. J. Pharmacol. Exp. Therap. 282:1345-1350.

Laughlin, TM, Kitto, KF and Wilcox, GL (1998) Redox manipulation of NMDA receptors in vivo: alteration of acute pain transmission and dynorphin-induced allodynia. Pain 80:37-43.

Roerig, S, Lei, S, Kitto, K, Hylden, JLK and Wilcox, GL (1992) Spinal interactions between opioid and noradrenergic agonists in mice: Multiplicitivity involves d and a2 receptors. J. Pharmacol. Exp. Ther. 262:365-374.

Stone, LS, Macmillan, L, Kitto, KF, Limbird, L and Wilcox, GL (1997) The a2a-adrenergic receptor subtype mediates spinal analgesia evoked by a2 agonists and is necessary for spinal adrenergic/opioid synergy. J. Neurosci. 17:7157-7165.

Velazquez, RA, Kitto, KF and Larson, AA (1997) CP-96,345, which inhibits [3H] substance P binding, selectively inhibits the behavioral response to intrathecally administered N-methyl-D-aspartate, but not substance P, in the mouse. J. Pharmacol. Exp. Therap. 281:1231-1237.



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